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论著:冠状动脉粥样硬化的非创伤性检测
Non Invasive Detection of Coronary Atherosclerosis
陈为君 林靖宇 张炜 董瑞芬 张新刚 陈璐 缪满
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作者单位:复旦大学附属中山医院心电图室
中文关键字:冠状动脉粥样硬化;踝臂脉搏波速度;眼底动脉粥样硬化
英文关键字:Coronary atherosclerosis; Brachial ankle pulse wave velocity; Retinal artery atherosclerosis
中文摘要:目的:探讨多种非创伤性检查方法评估冠状动脉粥样硬化的价值。方法:回顾分析240例体检疑似冠心病患者的资料,根据冠状动脉血管成像 (computed tomography angiography, CTA)结果分为冠状动脉粥样硬化组(n=132)和对照组(n=108);对所有患者进行踝臂脉搏波速度(brachial ankle pulse wave velocity,BaPWV)检测、眼底镜检查及双侧颈动脉彩超检查,并对其结果进行统计学分析。结果:BaPWV>1 400 cm/s 、颈动脉斑块硬化、眼底动脉粥样硬化≥2级在冠状动脉粥样硬化组中的比例显著高于对照组(P<0.05)。多变量Logistic回归显示BaPWV>1 400 cm/s、眼底动脉粥样硬化、吸烟史、年龄是冠状动脉粥样硬化的独立危险因素。结论:BaPWV检测与眼底镜检查作为无创、便捷、有效的检测手段,对体检中早期发现冠状动脉粥样硬化有重要价值。
英文摘要:Objective: To assess the value of some non invasive methods in the detection of coronary atherosclerosis. Methods: The clinical data of 240 subjects with suspected coronary diseases were reviewed. They were divided into the coronary atherosclerosis group(n=132) and the control group(n=108) according to the results of the coronary computed tomography angio graphy(CTA), The measurement of Brachial ankle pulse wave velocity (BaPWV), the eye fundus examination and carotid ultrasonography were conducted, and the results were compared. Results: The ratios of BaPWV>1 400 cm/s, carotid atherosclerosis and retinal artery atherosclerosis ≥stage 2 were significantly higher in the coronary atherosclerosis group than in the control group (P<0.05). Multivariate Logistic regressions showed that BaPWV>1 400 cm/s, retinal artery atherosclerosis, smoking and age were independent risk factors for coronary atherosclerosis. Conclusions: The measurement of BaPWV and the eye fundus examination are of great importance to the diagnosis of coronary atherosclerosis physical check up.
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