网络编辑平台

编辑出版

《中国临床医学》编辑部

  地址:上海市枫林路179号18号楼501室

  邮编:200032

  电话:021-60267570

  邮箱:(1)zglcyx@126.com; (2)zglcyxfb@126.com

作者园地

在线调查

您喜欢的投稿方式调查


相关下载

您所在位置:首页->过刊浏览->第18卷第6期


论著:射频消融联合经动脉化疗栓塞治疗肝癌的疗效分析
Transarterial Chemoembolization in Combination with Radiofrequency Thermal Ablation in Hepatocellular Carcinoma: a Systematic Review and Meta-analysis
孙贤俊 何胜利 沈婕 陈颢 陈越 蒋霆辉
点击:1342次 下载:0次
作者单位:复旦大学附属肿瘤医院闵行分院肝胆胰中西医结合科
中文关键字:肝癌;射频消融;经动脉化疗栓塞术;Meta分析;生存率
英文关键字:Hepatocellular carcinoma; Radiofrequency ablation; Transcatheter arterial chemoembolization; Meta-analysis; Survival rate
中文摘要:目的:比较经动脉灌注化疗栓塞(transcatheter arterial chemoembolization, TACE)联合射频消融(radiofrequency ablation, RFA)治疗肝细胞肝癌(hepatocellular carcinoma, HCC)与单独TACE或RFA治疗的临床远期疗效。方法:通过计算机和手工检索收集国内外关于TACE+RFA与单独TACE或RFA治疗无法手术切除肝癌的临床随机对照研究文献,并按Cochrane 协作网推荐的方法进行Meta分析。采用RevMan 4.2软件,对符合纳入标准的8个研究进行Meta分析。结果:联合治疗组的1、2、3年生存率显著优于单独治疗组(均P<0.05)。亚组分析结果显示:1年生存率联合治疗组和RFA组无显著差异;联合治疗组1、2、3年生存率显著优于TACE组(均P<0.01)。结论:TACE联合RFA治疗无法手术切除肝癌的远期疗效较单独治疗好,能有效提高患者生存率。
英文摘要:Objective: To compare the therapeutic effects of transcatheter arterial chemoembolization(TACE) plus radiofrequency ablation(RFA) to TACE or RFA alone for hepatocellular carcinoma (HCC). Methods: All data of patients with HCC underwent TACE+RFA versus TACE or RFA were collected from literature by electronic searching and handwork searching. Meta-analysis that recommended by Cochrane Collaboration was done for the data above, 8 researches enrolled in criteria were included in this study using RevMan 4.2. Results: Compared with that of TACE or RFA alone, 1-, 2-, 3- year survival in those underwent TACE+RFA was statistically higher (P<0.05), Subgroup analysis showed: TACE+RFA group in 1year survival rate was no significant difference in RFA group, Compared with that of TACE alone, 1-, 2-, 3-year survival in those underwent TACE+RFA was statistically higher(P<0.001). Conclusions: The prospective efficacy of TACE plus RFA for HCC which can elevate the patients’survival rate is better than that of TACE or RFA alone.
读者评论

      读者ID: 密码:   
我要评论:
主办单位:复旦大学附属中山医院
联系地址:上海市枫林路179号18号楼501室 邮编:200032
联系电话:021-60267570 E-Mail:(1)zglcyx@126.com; (2)zglcyxfb@126.com
版权所有©2009-2010 《中国临床医学》杂志编辑部 沪ICP备1103249号
本系统由北京菲斯特诺科技有限公司设计开发
您是本站第1269991名访问者