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论著:养血清脑颗粒对颅脑损伤后记忆障碍的影响
The Efficacy of Yangxue Qingnao Granule in Treatment of Brain Injury Induced Memory Decreasing
王玖飞 邢立举 徐丹
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作者单位:大庆油田总医院神经外科
中文关键字:养血清脑颗粒;颅脑损伤;精神状态判断法
英文关键字:Yangxue Qingnao granule;Brain injury;Psychitris status rating scales
中文摘要:目的:评价养血清脑颗粒对颅脑损伤后记忆减退的治疗作用。方法:选择颅脑损伤后记忆减退患者130例,随机分为养血清脑颗粒治疗组和常规治疗加淀粉对照组,每组各65例,两组在常规治疗的基础上分别服养血清脑颗粒和淀粉每次4.0 g,3次·d-1,共4周,于治疗前和治疗4周后进行记忆商的测定,同时进行不良反应的观察。结果:按临床疗效标准,养血清脑颗粒组总有效率87.7%,对照组为40.3%,两组经统计学分析示有显著差异(P<0.01)。患者的记忆力提高,养血清脑颗粒组平均增值17±11分,对照组平均增值5±7分,两组间比较P<0.01。养血清脑颗粒的不良反应较小。结论:养血清脑颗粒对颅脑损伤后的记忆减退有较好的恢复作用。
英文摘要:Objective: To evaluate the efficacy of yangxue qingnao granule in the treatment of brain injury induced memory decreasing.Methods: The total of 130 patients with brain injury induced memory decreasing were randomly divided to group one (receive yangxue qingnao granule in a regimen of 4.0 g tid for 4 weeks) and group two amylum in a regimen of 4. 0 g tid for 4 weeks). Both groups were evaluated the anamnesis before and 4 weeks after reatment, meanwhile, side effects were observed. Results: The total response rate was 87.7% for yangxue qingnao granule group and 40.3% for amylum group,there was significant difference between the two groups.The mean memory quotient increase was 17±9 for yangxue qingnao group and 5±7 for amylum group and there was significant difference between the two groups.Conclusion: Yangxue qingnao granule had an good effect on restoring memory decreasing induced by brain injury.Yangxue qingnao granule had less side effects.
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